Lipids and Lipid Derivatives
Apexbio Technology LLC 25-HYDROXYVITAMIN-D3-D3-1MG
25-Hydroxyvitamin D3-d3 (CAS No 140710-94-7) is a stable isotope-labeled analog of 25-hydroxyvitamin D3 used primarily in biomedical research It belongs to the category of vitamin D metabolites and is often employed to study the metabolism and function of vitamin D in biological systems Its mechanism of action involves binding to the vitamin D receptor (VDR) influencing calcium and phosphate homeostasis and modulating immune responses Commonly this compound displays activity in the nanomolar to low micromolar range in vitro It is frequently used in cellular models to understand vitamin D metabolism and in animal studies to evaluate pharmacokinetics Additionally it serves as a reference in drug screening assays to assess analogs efficacy and potency Experimental concentrations typically depend on the specific research design
Medchemexpress LLC Skatole-d3 | 111399-60-1 | 134.19 | 1 MG
Skatole-d3 is the deuterium labeled Skatole. It is produced by intestinal bacteria and regulates intestinal epithelial cellular functions by activating aryl hydrocarbon receptors and p38. It is for research use only. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC 1-Methyladenine-d3 | 15763-06-1 | 284.29 | 10 MG
1-Methyladenosine-d3 is the deuterium-labeled version of 1-Methyladenosine. 1-Methyladenosine is an RNA modification that can act as a tumor marker, with elevated levels linked to cancer development. The methylation of 1-methyladenosine leads to the upregulation of PPARδ expression, which regulates cholesterol metabolism and activates the Hedgehog signaling pathway, thereby promoting liver tumorigenesis.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by methods such as NMR, GC-MS, or LC-MS.
- Deuteration is used in drug molecules primarily as tracers for quantitation during drug development.
- Has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
Cayman Chemical 5 6-trns-VItamIn D3 10mg
An isomer of vitamin D3; increases tibia ash weight and bone mineralization in vitamin D-deficient chicks at 1, 3, and 10 UG/day; induces intestinal calcium transport and bone calcium mobilization in anephric rats fed a low-calcium and vitamin D-deficient diet at 25 UG/animal
Medchemexpress LLC Deapi-platycodin D3 | 67884-05-3 | 1 ML
Deapi-platycodin D3 is a triterpenoid saponin derived from the roots of Platycodon grandiflorum. This compound is intended for research use only.
- Purity: 98.86%
- Molecular weight: 1255.35
- Formula: C58H94O29
- Appearance: White to off-white solid
- Classification: Terpenoids, triterpenes
- Initial source: Plants, Campanulaceae, Platycodon grandiflorus (Jacq.) A. DC.
- Storage (solid): 4°C, protect from light
- Storage (in solvent): -80°C for 6 months; -20°C for 1 month (protect from light)
- Solubility (in vitro): DMSO 100 mg/mL (79.66 mM)
Medchemexpress LLC 7-methylguanosine-d3 | 00-00-0 | 98.5% | 301.29 g·mol⁻¹ | C11H13D3N5O5 | 5 MG
7-Methylguanosine-d3 is a deuterium-labeled stable isotope of 7-methylguanosine intended as a high-purity reference standard for analytical and biochemical applications. It is supplied in small-mass packages suitable for use in quantitative mass spectrometry, tracer studies, and method development. The unlabeled parent compound has reported activity against cNIIIB nucleotidase (IC50 = 87.8 ± 7.5 μM).
- High-purity deuterium-labeled isotopic standard for accurate mass spectrometry.
- Suitable as an internal standard for LC-MS or GC-MS quantitation.
- Useful for tracer studies and metabolic labeling experiments.
- Provided in small mass vials compatible with analytical workflows.
- Molecular formula C11H13D3N5O5; molecular weight 301.29 g·mol⁻¹.
Medchemexpress LLC Platycodin D2 | 66663-90-9 | 10 MM * 1 ML
Platycodin D2 is a saponin isolated from Platycodon grandiflorum, known for its anti-cancer activity and intended for research use only.
- High purity: 99.78%
- Molecular weight: 1387.46
- Appearance: Off-white to light yellow solid
- Exhibits antiproliferative activity against human HCT-15 and MES-SA cells
- Available as a 10 mM solution in DMSO
Medchemexpress LLC Glycine-2,2-d2, n-(1-oxobutyl)- | 1219799-10-6 | 99.2% | 147.17 g/mol | C6H9D2NO3 | 5 MG
N-Butyrylglycine-d2 is the deuterium-labeled form of N-butyrylglycine intended for laboratory research. It is provided as a high-purity isotopically labeled standard for use in analytical, tracer, and metabolic studies. The material is supplied with supporting analytical documentation and is for research use only.
- Deuterium-labeled (d2) isotopologue.
- High purity: 99.2% (nominal).
- Verified molecular weight: 147.17 g/mol.
- Chemical formula C6H9D2NO3.
- Certificates available: COA, HNMR, RP-HPLC, SDS.
- Available in small mg pack sizes suitable for analytical use.
Medchemexpress LLC N-Butyrylglycine-d2 | 1219799-10-6 | 99.17% | 147.17 | 10 MG
N-Butyrylglycine-d2 is the deuterium labeled N-Butyrylglycine. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. This compound is for research use only.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Cayman Chemical 4-hydroxy Nonal-d3 50ug
An internal standard for the quantification of 4-HNE by GC- or LC-MS